Central Roles and Regulatory Mechanisms of Dual-Specificity MAPK Phosphatases in Developmental and Stress Signaling

Mitogen-Activated Protein Kinase (MAPK) cascades are conserved signaling modules that integrate multiple signaling pathways.One bostik roll-cote level of control on the activity of MAPKs is through their negative regulators, MAPK phosphatases (MKPs).Therefore, MKPs also play an integrative role for plants responding to diverse environmental stimulu

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Inhibitor of Apoptosis (IAP) proteins in pediatric leukemia: Molecular pathways and novel approaches to therapy

Inhibitor of Apoptosis (IAP) proteins are a family of proteins with antiapoptotic functions that contribute to the evasion of apoptosis, a form of programmed cell death.IAP proteins are expressed at high levels in a variety of human cancers including childhood acute leukemia.This elevated expression has been associated with princess jasmine silhoue

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